Antirhe Active Pharmaceutical Ingredients and Intermediates Methotrexate; Powder API Methylaminopterin FDA GMP

• Customization: Available
• Function: Antibiotic and Antimicrobial Agents
• Grade Standard: Medicine Grade
• Model NO.: CAS NO: 59-05-2
• Type: Chemical Reagent
• Origin: China
• Production Capacity: 50tons

Product Description

GMPActive Pharmaceutical Ingredient Methotrexate API Methylaminopterin Antineoplastic and Antirhe

 

Product Name:  Methotrexate

Synonyms: Methotrexate;

                    Methylaminopterin;

                    Methylaminopterine;

                    antifolan;L-(+)-Amethopterin;

                    4-Amino-N 10-methylpteroyl-L-glutamic acid;

                    4-Amino-10-methylpteroyl-L-glutamic acid ;

                    (+)-4-Amino-10-Methylfolic acid; N-(p-(((2,4-Diamino-6pteridinyl)methyl)methylamino)benzoyl)-L-glutamic acid

 

CAS NO: 59-05-2

 

Specification: USP32-USP38

 

Molecular formula: C20H22N8O5

 

Molecular weight: 454.44

 

Appearance: Yellow or Orange crystal powder

 

Assay: 98%-102%

 

Usage: Used as a antineoplastic and antirheumatic. A folic Acid antagonist

 

Package: 1KG/bag, 5KG/bag, 25KG/drum

 

 

 

                                                 CERTIFICATE OF ANALYSIS

 

PRODUCT NAME	METHOTREXATE	BATCH NO.	20161003
QUANTITY	20KG	MAN.DATE	2016.10.26
TEST STANDARD	USP 32	EXP. DATE	2019.10.25

 

TEST	SPECIFICATION	RESULT
Appearance	Yellow crystalline powder	Conforms
Identification	IR , UV conform	Conforms
Rotation	+19°   -   +24°	+21.0°
Water	NMT 12.0%	10.5%
Residue on ignition	NMT  0.1%	0.05%
	Impurity C: NMT 0.5%	0.1%
	Impurity B: NMT 0.3%	0.09%
	Impurity E: NMT 0.3%	0.12%
	Any unspecified imp.: NMT 0.1%	0.07%
	Total unspecified imp: NMT 0.5%	Conforms
Assay	98.0 - 102.0%	99.5%
CONCLUSION: The product conforms to the standard of USP 32.