| Customization: | Available |
|---|---|
| Application: | Surgery |
| Usage Mode: | Intramuscular Administration |
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Amikacin sulfate is semi-synthetic aminoglycoside antibiotic derived from kanamycin. It is C22H43N5O13•2H2SO4•O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→4)-O-[6-amino-6-deoxy-α-Dglucopyranosyl-( 1→6)]-N3-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine sulfate (1:2)
Amikacin injection is used to treat serious bacterial infections in many different parts of the body. This medicine is for short-term use only (7 to 10 days).
Amikacin belongs to the class of medicines known as aminoglycoside antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.
Amikacin injection is usually used for serious bacterial infections for which other medicines may not work. However, it may also cause some serious side effects, including damage to your hearing, sense of balance, and kidneys. These side effects may be more likely to occur in elderly patients and newborn infants. You and your doctor should talk about the benefits of this medicine as well as the risks.
This medicine is to be administered only by or under the immediate supervision of your doctor.
A nurse or other trained health professional will give you this medicine. This medicine is given as a shot into a muscle or into a vein.
To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. Also, this medicine works best when there is a constant amount in the blood. To help keep the amount constant, you must receive this medicine on a regular schedule.
To keep your kidneys working well and help prevent kidney problems, drink extra fluids so you will pass more urine while you or your child are receiving this medicine.
Dosage for Amikacin Sulfate
The recommended dosage of Amikacin Sulfate Injection for adults, children and older infants with normal renal function is 15 mg/kg/day divided into 2 or 3 equal doses administered at equally-divided intervals, i.e., 7.5 mg/kg q12h or 5 mg/kg q8h. The usual duration of treatment is 7 to 10 days.
| DOSAGE GUIDELINES | ||||
| ADULTS AND CHILDREN WITH NORMAL RENAL FUNCTION | ||||
| Patient Weight | Dosage | |||
| lbs | kg | 7.5 mg/kg | 5 mg/kg | |
| q12h | OR | q8h | ||
| 99 | 45 | 337.5 mg | 225 mg | |
| 110 | 50 | 375 mg | 250 mg | |
| 121 | 55 | 412.5 mg | 275 mg | |
| 132 | 60 | 450 mg | 300 mg | |
| 143 | 65 | 487.5 mg | 325 mg | |
| 154 | 70 | 525 mg | 350 mg | |
| 165 | 75 | 562.5 mg | 375 mg | |
| 176 | 80 | 600 mg | 400 mg | |
| 187 | 85 | 637.5 mg | 425 mg | |
| 198 | 90 | 675 mg | 450 mg | |
| 209 | 95 | 712.5 mg | 475 mg | |
| 220 | 100 | 750 mg | 500 mg | |
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