Product name: Omeprazole
Contains: 40mg
Description:
Omeprazoleis a proton pump inhibitor used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger-Ellison syndrome.
Omeprazole is one of the most widely prescribed drugs internationally and is available over-the-counter in some countries.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.
Omeprazole 40 mg/vial IV Injection belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, omeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.
Application:
Omeprazole can be used in the treatment of gastroesophageal reflux disease, peptic ulcers, erosive esophagitis, and Zollinger-Ellison syndrome.
Shelf life
Powder for solution for infusion: 2 years.
Reconstituted solution: Chemical and physical in-use stability has been demonstrated for 12 hours when dissolved in NaCl 0.9% solution and for 6 hours in 5% glucose when reconstituted under controlled aseptic conditions and stored below 25° C.
Chemical and physical in-use stability has also been demonstrated for 24 hours at 2-8° C in both NaCl 0.9% solution and 5% glucose.
From a microbiological point of view, the product should be used immediately.
If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2 to 8 ° C, unless reconstitution has taken place in controlled and aseptic conditions.
Audited Supplier 
){kind=link}