| Application: | Internal Medicine |
|---|---|
| Usage Mode: | For external use |
| Suitable for: | Elderly, Children, Adult |
| State: | Liquid |
| Shape: | Injection |
| Type: | Biological Products |
| Customization: |
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Audited Supplier Character:A colorless and transparent liquid.
Indications:
For acute and chronic cerebral vascular disease, brain injury, all kinds of toxic encephalopathy and other causes of memory loss and light, moderate brain dysfunction. It is also used for children's intelligence development retardation.
[name]Piracetam Injection
English Name: Piracetam Injection
Chinese Pinyin: Bilaxitan Zhusheye
[ingredients] the main ingredients of this product are: piracetam; accessories: sodium chloride, water for injection.
Chemical name: 2- oxidation of -1- pyrrolidone.
Chemical structural formula:
Molecular formula: C6H10N2O2
Molecular weight: 142.16
[properties] this product is a colorless and transparent liquid.
[indications] for acute and chronic cerebrovascular disease, brain trauma, a variety of toxic encephalopathy and other causes of memory loss and mild to moderate brain dysfunction. Children with mental retardation.
[Specification] 5ml:1g
[usage] intramuscular injection, each 1g, 2 ~ 3 times a day.
Intravenous injection, every time 4 ~ 6G, a day of 2 times.
Intravenous drip, every time 4 ~ 8g, a day of 1, with a 5% or 10% Glucose Injection or Sodium Chloride Injection diluted to use after 250ML.
[1] the common adverse reactions, gastrointestinal adverse reactions are nausea, anorexia, abdominal discomfort, abdominal distension, abdominal pain and other symptoms, the severity and the dose is directly related to the.
2, the central nervous system adverse reactions, including excitement, irritability, dizziness, headache and insomnia, etc., but the symptoms are mild, and with the use of the size of the dose has nothing to do, after stopping the above symptoms disappear.
3, occasionally mild liver function damage, showed mild aminotransferase increased, but not with the drug dose.
[taboo]
1 extrapyramidal diseases, Huntington disease, disabled.
2, pregnant disabled.
3, neonatal disabled.
[note] liver and kidney dysfunction should be used with caution and appropriate dose reduction.
[pregnant and lactating women medication] 1, this product is easy to pass through the placenta barrier, so pregnant women disable.
2, lactating women medication is not clear.
[child medication] disabled newborn.
Elderly medication is not clear.
[drug interaction] this drug interaction combined with warfarin, prolonged prothrombin time, can induce the inhibition of platelet aggregation, in patients receiving anticoagulant therapy, at the same time the application of this product should pay special attention to prevent the risk of bleeding, clotting time, and adjust the dosage and usage of anticoagulant drugs.
Drug overdose is not clear.
[pharmacology and toxicology]
1, pharmacology
This product is an improvement of brain metabolism drugs, belonging to Y- amino acid derivatives of the ring. The effects of physical and chemical factors on brain damage. Can promote brain ATP. It can promote the synthesis of acetylcholine and enhance the conduction of nerve excitability. It can be used to combat brain damage caused by physical and chemical factors. Effect of hypoxia on retrograde amnesia. Can enhance memory, improve learning ability.
2, toxicology
Acute toxicity test of animal experiment. There was no death in mice with gastric dose greater than 10g/kg, and the median lethal dose of LD50 was 9.2g/kg. Subacute and chronic toxicity tests were not found to have any adverse effects on the growth and development of rats and dogs. It had no effect on the blood, heart, liver, kidney, brain and other important organs and functions.
After the product enters the blood, through the blood-brain barrier to reach the brain and cerebrospinal fluid, cerebral cortex and olfactory bulb concentrations higher than the concentration of brain stem. Placenta barrier. Half life (t1/2) 5 ~ 6 hours, body distribution capacity of 0.6L/kg, renal elimination rate of 86 ml/ minutes.
[packing] low borosilicate 5 glass ampoule / box
[Storage]
Protectd from light, temperature below 30°C.
keep out of reach of children.
[validity period] Three years
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