| Varieties: | Growth Promoting Medicine |
|---|---|
| Component: | Animal |
| Type: | The First Class |
| Storage Method: | Light Proof |
| Origin: | China |
| Customization: |
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Description
This product is colorless transparent liquid.
Function and use
This product can effectively dissolve functional corpus luteum plus pathological corpus luteum and strengthen systolic and diastolic rhythms of uterine smooth muscles.
It is commonly applied :
1. To cure failure to come into estrus due to persistent corpus luteum or corpus luteum cysts.
2. In estrus synchronization and estrus control
3. In parturition control such as odinopoeia and abortion.
4. In postpartum care , preventing and curing puerperal endometritis and promoting ovarian and uterus recovery.
This product is an artificially synthesized homologue of prostaglandin F2a. It is able to cause quick regression of corpus luteum with strong luleolytic effect and suppress its secretion ; It can cause contraction of uterine smooth muscles and cervical relaxation sine it has a direct excitatory effect on uterine smooth muscles. Generally , animals with normal sexual sycle will be in estrus 2 to 5 days after treatment and cattle that are 10 to 150 days pregnant will miscarry 2 to 3 days after injection of this product.
In veterinary clinical practice , this product can be used to induce estrus synchronization for female animals, cure diseases such as persistent corpus luteum , corpus luteum cysts and follicular cysts for femal cattle; It also can be applied in parturition synchronization for pregnant sows or eves as well as the treatment of uterus subinvolution , retained fetal membranes , endometritis and pyometra after delivery.
It has luleclytic effect and is mainly used to control estrus synchronization for femal cattle and induce
parturition for pregnant sows.
Usage and Dosage
5ml intramuscular injection for cattle
2ml intramuscular injection for swine
Indications
1. More effectively control cattle's estrus cycle and ovulation
2. Treat cattle that has functional corpus luteum but no estrus appearance ( recessiveness estrus)
3. To induce cattle abortion
4. To induce cattle parturition
5. To treat cattle chronic womb inflammation and pyometra
6. To control cattle breeding
Application in Cattle Reproduction
1. Estrus synchronization: There are two methods as follow:
a. Single-injection method. 40%-70% of the female cattle will come into estrus 3-5 days after intramuscular injection of 0.2mg of Cloprostenol Sodium on any day during their estrus cycle. It has no effect on lower rate of estrus synchronization.
b. Double-injection method. Breeding is not implemented for estrous cattle after the first injection of Cloprostenol Sodium and the dosing shall be repeated once after an interval of 11-12 days. 3 to 5 days later, 40%-70% of the treated female cattel will come into estrus. Either method can make the estrous pregnancy rate reach over 50%.
2. Timed Artificial insemination for cows:
Method 1: the cows should be treated with 100μg of shuniu GnRH first , injected 0.2-0.3mg of Cloprostenol Sodium after 7 days and then injected 100μg of Shuniu GnRH 48 hours later. Estruses of the cows don't need to be observed , they can just be implemented breeding 18-20 hours after the second injection of Shuniu GnRH.
Method 2: The cows should be injected Cloprostenol Sodium twice before implementing Method 1 with an interval of 14 days , 0.2-0.3mg for each; 12 days after the second injection of Cloprostenol Sodium , the cows are treated with Method 1. This process can start 35-40 days after the delivery of the cows. and breeding can be implemented 70-75 days after delivery. The pregnancy rate is higher than that of Method 1.
3. Estrus induction: It has special effects on non-pregnancy of female cattle due to functional corpus luteum , persistent corpus luteum and corpus luteum cysts. Intrauterine input of 0.1mg of Cloprostenol Sodium or intramuscular injection of 0.2mg should be implemented within 5-14 days of the cycle.
4. Treatment of persisten corpus luteum and corpus luteum cysts: intramuscular injection of 0.2mg of Cloprostenol Sodium; half of the dose for intrauterine injection.
5. Treatment of uterine diseases ( subinvolution of uterus due to retained fetal membranes , prolonged lochia. Pyometra , uterine hydrops and endometritis of cattle) : intramuscular injection of 0.2mg of Cloprostenol Sodium; half of the dose for intrauterine injection. If the first treatment is not ideal , the second injection can be implemented 10-14 days later. When cooperatively used with Ceftiofur Sodium, it can inhibit and kill pathogens , exerting better effect. After curing, breeding only can be implemented in the second estrus.
6. Promoting the recovery of ovary and uterus after delivery and shortening the calving interval : intramuscular injection of 0.2mg of Cloprostenol Sodium within 2-5 days after delivery; once a day for 2-3 consecutive days. It can promote the recovery of ovary and uterus after delivery and prevent endometritis.
7. Shortening postpartum non-pregnant period : intramuscular injection of 0.2mg of Cloprostenol Sodium about 30 days after delivery can shorten the cattle's first estrus after deliver and improve the pregnancy rate. Intramuscular injection of 100μg of Shuniu (GnRH) on the 40th day after delivery , intramuscular injection of 0.2mg of Cloprostenol Sodium on the 47th days and intramuscular injection of 100μg of Shuniu (GnRH) on the 49th day can improve the pregnancy rate within 90 days obviously.
8. Odinopoela and abortion: Intramuscular injection of 0.2mg of Cloprostenol Sodium for female cattle with abrnormal pregnancy ( stillibirth , weak feluses or mismatch ). Some cows need continuous injections for a few days until miscarriage. It has a better effect on induced labor when cooperatively used with estradiol benzoate and oxytocin during mid and late pregnancy.
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